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Phenibut HCL safety data sheet on a laboratory workstation

How Do You Read A Safety Data Sheet For Phenibut HCL?

Written By: Neat Digital, Research Content Writer

Reviewed By: Natalie Kunsman, M.D., Board-Certified Physician

Last Reviewed: October 9, 2026

 

Diclaimer. Nordic Chems sells Phenibut HCL (CAS 3060-41-1) strictly for laboratory research and educational purposes. It is not for human consumption. This article explains how to read a safety data sheet. It isn't guidance for any use outside a controlled research setting.

Read a phenibut HCL safety data sheet in this order. Confirm what the material is in Sections 1 and 3. Read the hazard classes in Section 2. Then pull storage and PPE rules from Sections 7 and 8, and the revision date from Section 16. OSHA requires all 16 headings in a fixed order, but it doesn't enforce the content of Sections 12 to 15. Finish by checking the SDS against 2 outside records: the certificate of analysis (COA) for your batch and your state's controlled substance schedule.

Don't assume 2 SDSs for the same material agree. In September 2026, we compared 3 SDSs for CAS 3060-41-1: ours and 2 from other suppliers. Only 1 lists acute toxicity, and the 3 label eye irritation 3 different ways.

A phenibut HCL safety data sheet (SDS) is the supplier's 16-section hazard document for 4-amino-3-phenylbutanoic acid hydrochloride, CAS 3060-41-1. It names the material and its supplier, classifies its hazards, and lists first aid, storage, PPE, spill, and disposal instructions. OSHA's rules set the section order, and Section 16 dates the document.

Phenibut is studied in GABAergic signaling and receptor pharmacology research. Whatever the study design, everyone at the bench should read the SDS before the container is opened.

Sixteen-section safety data sheet layout

What Does Each Section of a Phenibut HCL Safety Data Sheet Cover?

Each of the 16 sections answers 1 question about the material, in an order OSHA fixes. OSHA enforces the content of Sections 1 to 11 and 16. Sections 12 to 15 still need their headings, to match the GHS (Globally Harmonized System). But OSHA doesn't enforce what's in them, since those areas are outside its jurisdiction.

Here's what each section says on the SDS for our 50-gram Phenibut HCL powder, revision 001, dated May 14, 2025.

Section

Heading

OSHA enforces content?

What our Phenibut HCL SDS shows

1

Identification

Yes

Trade name, synonym, supplier, and "Research use only"

2

Hazard(s) identification

Yes

Signal word "Warning" plus H315, H319, and H335

3

Composition/information on ingredients

Yes

4-Amino-3-phenylbutyric acid hydrochloride, CAS 3060-41-1

4

First-aid measures

Yes

Steps for each exposure route

5

Fire-fighting measures

Yes

Dry chemical, CO2, water spray, or alcohol-resistant foam

6

Accidental release measures

Yes

Avoid generating dust and keep the material out of drains

7

Handling and storage

Yes

Cool, dry, well-ventilated storage

8

Exposure controls/personal protection

Yes

Mechanical exhaust, gloves, goggles, and a respirator

9

Physical and chemical properties

Yes

Powder with a melting range of 194.0 to 202.0°C

10

Stability and reactivity

Yes

"No data available" on the reactivity lines

11

Toxicological information

Yes

Skin and eye exposure named as most likely

12

Ecological information

No

"No statements available"

13

Disposal considerations

No

The waste generator makes the hazardous waste call

14

Transport information

No

Non-regulated

15

Regulatory information

No

U.S. federal lists, Canada's DSL, and California Prop 65

16

Other information

Yes

Revision 001, May 14, 2025

 

Start with identity, even though Section 2 gets the attention. Every hazard line describes the material named in Section 3. If that CAS number is wrong, the rest of the sheet may describe a different material.

Keep the SDS where your team can reach it. Under OSHA's Laboratory Standard (29 CFR 1910.1450), employers have to keep the SDSs that arrive with incoming shipments of hazardous chemicals. Those SDSs must be readily accessible to lab employees. Electronic copies are allowed under the Hazard Communication Standard, as long as they don't create barriers to immediate employee access.

SDS Section 1 identification details

Start With Identity: Sections 1 and 3

Sections 1 and 3 tell you what the material is and who stands behind the document. Check both before you trust any other line.

Our Section 1 lists the trade name, the synonym 4-Amino-3-phenylbutyric acid hydrochloride, and Nordic Chems as the supplier. Under Appendix D of OSHA's Hazard Communication Standard, Section 1 has to carry 5 items:

•      the product identifier used on the label

•      other means of identification

•      the recommended use and restrictions on use

•      the name, address, and telephone number of the responsible party

•      an emergency phone number

Where research-use-only status lives on the SDS

Section 1 is where a supplier states what the material is for. Ours lists "Research use only" as the identified use and "All other uses" under uses advised against.

That line matches how we sell. Before checkout, buyers read our full terms of service and confirm they're professionals trained to handle these chemicals. We vet every order before it ships and permanently ban anyone who breaks those terms.

Section 3: match the CAS number and salt form

Section 3 names the chemical and its CAS number. For Phenibut HCL, that's CAS 3060-41-1, the hydrochloride salt. PubChem lists it as C10H14ClNO2 (CID 11499499), which works out to about 215.7 g/mol. Phenibut free base is a separate entry: CAS 1078-21-3, C10H13NO2, 179.22 g/mol. Our powder page and our Phenibut product page both list CAS 3060-41-1.

Match that CAS number in 3 places: the SDS, the container label, and the COA. If any of them points to the free base, stop and ask the supplier which form you received. The 2 forms sit about 36.5 g/mol apart, and that gap changes every concentration you calculate.

Safety Data Sheet hazard identification section

What Hazards Does Section 2 List for Phenibut HCL?

Our SDS lists Phenibut HCL as a skin, eye, and respiratory tract irritant. The signal word is "Warning," and each hazard class has 1 hazard statement.

Code

Hazard statement on our SDS

Hazard class and category

H315

Causes skin irritation

Skin irritation, Category 2

H319

Causes serious eye irritation

Eye irritation, Category 2

H335

May cause respiratory irritation

Specific target organ toxicity, single exposure, Category 3

 

Those categories have fixed definitions, set out in Appendix A of OSHA's Hazard Communication Standard. A skin irritant is a substance that "produces reversible damage to the skin following its application for up to 4 hours." For eyes, Category 2A applies when irritation reverses within an observation time of normally 21 days. Category 2B applies when it reverses within 7 days. A plain Category 2, the label on our SDS, uses the same criteria as 2A.

Precautionary statements, the P-codes, are the instructions. Ours include P261 (avoid breathing dust) and P280 (wear protective gloves, protective clothing, eye protection, and face protection). P305+P351+P338 reads "IF IN EYES: Rinse cautiously with water for several minutes." P501 points disposal to local, regional, national, and international regulations.

Section 11 backs up Section 2. It names skin and eye exposure as "the most likely to occur" and repeats the respiratory irritation statement.

Sections 4 to 6: First Aid, Fire, and Spills

Sections 4 to 6 are the emergency sections. Read them before the container is opened, while nothing is going wrong.

For skin contact, our SDS says to "Wash immediately with plenty of water and soap for at least 15 minutes" and to remove contaminated clothing and shoes. For eye contact, it says to flush with plenty of flowing water "for 10 to 15 minutes holding eyelids apart."

Section 5 lists dry chemical, CO2, water spray, or alcohol-resistant foam for a fire, and it warns of toxic fumes. Section 6 says to avoid generating dust, cover drains, and keep the material out of soil, surface water, and drains. With a powder, most of Section 6 comes down to dust control.

SDS storage handling and PPE information

Sections 7 and 8: Storage, Handling, and PPE

Section 7 covers how to store and handle the material, and Section 8 covers the controls and gear that go with it. Our SDS gives no storage temperature and no exposure limit, so the exact wording in both sections matters.

Our Section 7 says to avoid contact with skin, eyes, and clothing and to avoid prolonged or repeated exposure. For storage, it reads "Store in a cool, dry, well-ventilated area," away from incompatible substances.

Storage starts before the container reaches you. We induction-seal and desiccate our chemicals before they ship, in tamper-evident packaging. After delivery, our guide to storing phenibut covers temperature and humidity.

Section 8 lists "No data available" for exposure limits. For engineering controls, it calls for mechanical exhaust plus a safety shower and eye shower. For PPE, it lists suitable gloves, protective eyeglasses or chemical safety goggles as described by OSHA, protective clothing, and a NIOSH/MSHA or European Standard EN 149 approved respirator.

"Suitable gloves" isn't a glove specification. Our SDS doesn't name a glove material, so that choice belongs to your environmental health and safety (EHS) office or chemical hygiene officer. A blank exposure limit gives you no number to work against, which puts more weight on the engineering controls.

What Does "No Data Available" Mean on an SDS?

"No data available" means the supplier had no data for that line when it wrote the SDS. It doesn't mean anyone tested the material and ruled the hazard out.

OSHA's Hazard Communication Standard says so: "There is no requirement to test the chemical to determine how to classify its hazards." Suppliers work from the data they have.

Research-grade materials often come with thin data. On our SDS, Section 10 lists "No data available" for reactivity, chemical stability, hazardous reactions, conditions to avoid, and incompatible materials.

When a line is blank, pull another supplier's SDS for the same CAS number. For CAS 3060-41-1, a U.S. supplier's SDS revised October 30, 2025 lists strong oxidizing agents as incompatible. It names carbon dioxide, carbon monoxide, hydrogen chloride, and nitrogen oxides as hazardous decomposition products. Until you have better data, log an empty line as unknown.

Why Can 2 SDSs for CAS 3060-41-1 List Different Hazards?

Each supplier classifies the material from the data it holds, and OSHA doesn't require testing. So 2 SDSs for the same CAS number can carry different hazard classes.

We compared our SDS with 2 others for CAS 3060-41-1 in September 2026.

Classification

Nordic Chems SDS

Supplier B (U.S.)

Supplier C

Revision date

May 14, 2025

October 30, 2025

October 16, 2023

Signal word

Warning

Warning

Warning

Skin irritation

Category 2

Category 2

Category 2

Eye irritation

Category 2

Category 2A

Category 2B

Single-exposure target organ toxicity

Category 3

Category 3

Not listed

Acute toxicity

Not listed

Not listed

Category 4, 3 exposure routes

Hazard statement codes

H315, H319, H335

H315, H319, H335, H336

H302, H312, H332, H315, H320

 

All 3 agree on skin irritation and the signal word. The eye category shifts between 2, 2A, and 2B, and only Supplier C lists acute toxicity. Under OSHA's criteria, the 2A and 2B split turns on whether irritation reverses within normally 21 days or within 7.

That spread is why we read an SDS as 1 supplier's classification call. OSHA also gives preparers 3 months to add newly learned significant hazard information, so a classification can change between revisions. When SDSs for the same CAS number disagree, bring the stricter classification to your EHS office and let them set the controls.

An SDS won't tell you what's in your specific container. Batch testing does that job.

SDS and certificate of analysis batch records

How Do You Match the SDS to Your Certificate of Analysis?

The SDS describes the substance, and the COA describes your batch. Match them on CAS number and salt form first, then on batch number and test date.

1.       Confirm that the SDS, the container label, and the COA all identify Phenibut HCL, CAS 3060-41-1.

2.       Find the batch or lot number on the COA and match it to your container.

3.       Read the methods and the test date. Purity should come from a method like HPLC, and identity from mass spectrometry.

4.       Keep both dates on file. The COA test date and the SDS revision date answer different questions, so a new COA doesn't update an old SDS.

 

Email support@nordicchems.is with your order number, and we'll tell you which batch it came from. Our batches are tested by BioRegen Labs in Houston, Texas, or Janoshik Analytical in Prague, Czech Republic, with HPLC and mass spectrometry. We don't use any batch that tests below 99% purity, and we've put 20 batches through third-party testing so far.

Our phenibut COA guide walks through each certificate check, including the salt-form math.

Sections 12 to 16: Disposal, Transport, Regulations, and the Revision Date

Sections 12 to 15 keep their headings, but OSHA doesn't enforce their content. Section 16 is required, and its date tells you how current everything above it is.

On our SDS, Section 12 reads "No statements available" for ecological data. Section 13 says the chemical waste generator has to determine whether a discarded chemical is classified as hazardous waste. Bring that call to your EHS office. Section 14 lists the material as non-regulated for transport.

Section 15 won't keep up with state law

Section 15 is a snapshot from the revision date, and OSHA doesn't enforce it. State scheduling can change after an SDS is written.

Utah's H.B. 173 added phenibut to Schedule I as of May 7, 2025. Connecticut's Department of Consumer Protection issued guidance for businesses that lists phenibut as a Schedule I controlled substance. It set a March 25, 2026 deadline to destroy or return products.

The Section 15 on our SDS covers U.S. federal lists, Canada's DSL, and California Prop 65. It doesn't track state scheduling, so we track that outside the SDS. Our product page lists Alabama, Utah, and Connecticut as restricted states, and our shipping profiles keep restricted chemicals from going to those states. Check your own state's schedule. Section 15 won't do it for you.

What the Section 16 revision date tells you

Section 16 gives the date the SDS was prepared or last changed. Ours is revision 001, dated May 14, 2025.

OSHA updated its Hazard Communication Standard in a final rule published May 20, 2024. In a January 15, 2026 Federal Register notice, OSHA extended the compliance dates for that update. The date for manufacturers, importers, and distributors of substances moved to May 19, 2026. For employers working with substances, it's November 20, 2026.

If your lab's copy predates May 20, 2024, ask the supplier for the current revision. A 2015 OSHA interpretation letter says the manufacturer or importer has to provide the updated SDS with the first shipment after an update, or on request.

Researcher completing a Phenibut HCL SDS checklist beside SDS, COA, and a sealed laboratory container

Your 2026 Checklist for a Phenibut HCL SDS

Run these 8 checks whenever a new SDS or a new batch arrives.

1.       Match CAS 3060-41-1 across the SDS, the container label, and the COA.

2.       Read the recommended use in Section 1. Ours says research use only.

3.       List every hazard statement in Section 2, along with the signal word.

4.       Pull the engineering controls and PPE from Section 8 before anyone opens the container.

5.       Log each "No data available" line as unknown.

6.       Compare Section 2 with a second supplier's SDS for the same CAS number.

7.       Check your state's controlled substance schedule instead of relying on Section 15.

8.       Record the Section 16 revision date and the COA test date with your batch records.

 

Research Use Only

Nordic Chems sells Phenibut HCL for laboratory research and educational purposes only. It is not for human consumption. Our buyers include professional researchers, universities, wholesalers, and analytical labs.

We don't give directions or advice on how to use a chemical. That decision belongs to the trained researcher and your institution's safety office. We explain why phenibut stays research-only in a separate post.

Read the phenibut HCL safety data sheet before the container is opened, and file it with your batch records.


Frequently Asked Questions

 Where can I find the phenibut HCL safety data sheet from Nordic Chems?

The SDS is linked on our Phenibut HCL powder and Phenibut product pages. The current version is revision 001, dated May 14, 2025, and it covers 4-amino-3-phenylbutyric acid hydrochloride, CAS 3060-41-1. Section 1 lists the recommended use as research use only.

What hazards are listed on a phenibut HCL safety data sheet?

Our SDS lists 3 hazard statements under the signal word "Warning": H315 (causes skin irritation), H319 (causes serious eye irritation), and H335 (may cause respiratory irritation). Other suppliers' SDSs for CAS 3060-41-1 can differ. In our September 2026 comparison, 1 of 3 SDSs also listed acute toxicity, Category 4.

Which sections of an SDS does OSHA require?

OSHA requires all 16 section headings in a fixed order. It enforces the content of Sections 1 to 11 and Section 16. It doesn't enforce the content of Sections 12 to 15, which cover ecological, disposal, transport, and regulatory information, because those areas aren't under its jurisdiction.

Why do SDSs for CAS 3060-41-1 list different hazards?

Suppliers classify hazards from the data they hold, and OSHA's Hazard Communication Standard says there is no requirement to test a chemical to classify its hazards. The 3 SDSs we compared label eye irritation as Category 2, 2A, and 2B. Only 1 of them lists acute toxicity.

 What's the difference between an SDS and a certificate of analysis?

An SDS covers the hazards and handling of a substance, while a certificate of analysis reports identity and purity for 1 batch. Nordic Chems batches are tested by BioRegen Labs or Janoshik Analytical, and we don't use any batch below 99% purity. Send us your order number to find out which batch you received.

How often does a safety data sheet have to be updated?

OSHA gives the preparer 3 months to add newly learned significant information about a chemical's hazards or ways to protect against them. A 2015 OSHA interpretation letter says the updated SDS goes out with the first shipment after the update, or on request. Check the Section 16 revision date each time a new copy arrives.

Does a phenibut HCL SDS show state restrictions?

Don't count on it. Section 15 is a snapshot from the revision date, and OSHA doesn't enforce its content. Utah added phenibut to Schedule I as of May 7, 2025, and Connecticut set a March 25, 2026 deadline for businesses to destroy or return phenibut products. Nordic Chems doesn't ship Phenibut HCL to Alabama, Utah, or Connecticut.

How Should Labs Perform Sieve Analysis On Phenibut HCL Powder?
Scientist examining molecular research in a modern laboratory.

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